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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC63
All Species:
32.42
Human Site:
Y446
Identified Species:
59.44
UniProt:
Q8NA47
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NA47
NP_689804.1
563
66250
Y446
T
D
I
N
L
P
Q
Y
F
A
I
I
E
K
K
Chimpanzee
Pan troglodytes
XP_509370
563
66213
Y446
T
D
I
N
L
P
Q
Y
F
A
I
I
E
K
K
Rhesus Macaque
Macaca mulatta
XP_001100621
223
26551
I124
L
A
E
L
D
E
K
I
V
E
M
E
K
K
I
Dog
Lupus familis
XP_534677
558
65244
Y447
T
D
N
N
L
P
Q
Y
F
A
I
V
E
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDV6
558
65255
Y443
T
D
I
N
L
Q
Q
Y
F
A
I
I
E
K
K
Rat
Rattus norvegicus
Q4V8F7
559
66089
Y443
T
D
S
N
L
Q
Q
Y
F
A
I
I
E
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506125
545
64339
F430
K
D
N
N
L
A
H
F
F
A
I
I
E
K
K
Chicken
Gallus gallus
XP_415165
550
63725
Y445
T
D
L
N
L
M
Q
Y
L
G
L
V
E
K
K
Frog
Xenopus laevis
NP_001083612
559
64752
Y444
R
E
T
N
I
M
Q
Y
L
G
L
I
E
Q
K
Zebra Danio
Brachydanio rerio
NP_001007409
566
66367
Y445
R
D
S
N
I
M
T
Y
L
S
L
V
E
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394326
522
61249
Y410
T
M
S
N
V
M
L
Y
L
G
I
I
E
K
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789929
570
65774
Y448
T
D
D
T
I
M
Q
Y
L
G
L
V
E
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C9Z8
235
26834
E136
S
V
L
L
R
C
R
E
M
D
K
K
V
V
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
37.1
76.3
N.A.
72.1
70.8
N.A.
56.1
43.8
29.3
28.2
N.A.
N.A.
25.3
N.A.
29.4
Protein Similarity:
100
99.6
38.5
88
N.A.
87.5
83.4
N.A.
73.5
66.7
52.9
53.5
N.A.
N.A.
47.4
N.A.
51.7
P-Site Identity:
100
100
6.6
86.6
N.A.
93.3
86.6
N.A.
66.6
60
40
26.6
N.A.
N.A.
46.6
N.A.
33.3
P-Site Similarity:
100
100
26.6
93.3
N.A.
93.3
86.6
N.A.
73.3
80
66.6
66.6
N.A.
N.A.
60
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
30.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
0
0
47
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
70
8
0
8
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
8
8
0
0
8
0
8
0
8
0
8
85
0
8
% E
% Phe:
0
0
0
0
0
0
0
8
47
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
31
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
24
0
24
0
0
8
0
0
54
54
0
0
8
% I
% Lys:
8
0
0
0
0
0
8
0
0
0
8
8
8
70
62
% K
% Leu:
8
0
16
16
54
0
8
0
39
0
31
0
0
0
0
% L
% Met:
0
8
0
0
0
39
0
0
8
0
8
0
0
0
0
% M
% Asn:
0
0
16
77
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
24
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
16
62
0
0
0
0
0
0
24
8
% Q
% Arg:
16
0
0
0
8
0
8
0
0
0
0
0
0
0
16
% R
% Ser:
8
0
24
0
0
0
0
0
0
8
0
0
0
0
0
% S
% Thr:
62
0
8
8
0
0
8
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
8
0
0
0
8
0
0
31
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _